Fibromyalgia is a disease of death
Although there are many ongoing speculations about what triggers fibromyalgia, its causes have not yet been definitively identified and confirmed. Recent research has generally found that fibromyalgia is most likely the result of what scientists call the central consciousness, or unusual reactions in the nervous system regarding the perception of pain.
biochemical triggers of fibromyalgia
“The [current] consensus is that fibromyalgia is not a problem with muscles, joints or tendons, but rather a problem with the central nervous system,” says Dr. Bruce Solitar, associate professor of medicine in the division clinic. of rheumatology at the New York University Medical Center / hospital for Joint Diseases in New York. While it is easy to think that the pain felt by someone who did not suffer physical damage to the body could be classified as purely psychosomatic sensations that the patient experiences fibromyalgia are as real as any other pain.
This was clearly demonstrated when the researchers made magnetic resonance imaging of patients with fibromyalgia. When they pressed on certain areas of the participants’ bodies, they found dramatic increase in activity in the brain’s pain center. One theory attributes to an increase in the release of substance P, the chemical that activates the nerves when there is a painful stimulus. “In patients with fibromyalgia, substance P is released, even in the absence of a painful stimulus. And there seems to be an amplified version when there is a painful stimulus, “says Dr. Solitar. In addition, the regulating effect of the brain, which sends “signals down” to quench pain, also seems to be abnormal in people with fibromyalgia – when a painful stimulus occurs,
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Physical and emotional triggers of fibromyalgia
What causes the nervous system to function badly? Scientists are not sure, but a number of conditions have been linked to the development of fibromyalgia. These include:
The infection. The Epstein-Barr viruses that cause influenza and hepatitis B and C have been implicated in the development of fibromyalgia. “These viruses may have [long-term] effects on the immune system. It is also possible that viral particles bind to glial cells, which are the cells in the brain that affect the neurotransmission [and influence the pain response],” says Dr. Solitar. In addition, there is a well-established relationship between Lyme disease (caused by a bacterium called Borrelia burgdorferi) and Fibromyalgia: Some patients who have received treatment for Lyme – and apparently recover from it – continue to face an abnormally high frequency unprovoked pain that characterizes fibromyalgia.
Trauma. Sometimes, the development of fibromyalgia is related to physical injury, particularly in the upper (cervical) spine. In other cases, it is associated with great emotional stress, such as the death of a family member or the loss of a job. The possible relationship between these types of self-injury is the neurohormonal changes that both physical injuries and emotional stress can trigger. The psychological processes can change – and can be modified – alterations in the function of regulating the centers of hormones such as the hypothalamus and the hypophysis and suprarenal lesglandes, which in turn can affect the nervous system.
Other common issues of fibromyalgia
“Fibromyalgia is associated with all age groups, although women between the ages of 30 and 50 have a higher incidence of the disease,” says Dr. Solitar. Although this increase in prevalence in young women suggests a hormonal relationship, it says that it is also possible that this is related to the diagnosis. “Women tend to [naturally] tender [or sensitive to pain] than men, so if you base your diagnosis on tender points, you’re likely to diagnose fibromyalgia with more women than men.”
In addition, fibromyalgia often develops in several members of the same family, but it is not clear whether this is the result of genetic or environmental effects. “The relatives of people with fibromyalgia seem to be more sensitive than others,” says Dr. Solitar, “but there is not much conclusive genetic research there.”
In many cases, the reason for fibromyalgia strikes is still largely unknown . “For many patients,